I wouldn't be surprised if this ended up being the case, especially in the short term.
In the medium term to long term? Who knows. Maybe still true.
Against different variants? Who knows. Maybe still true.
It's hubris to assume that we know much at the moment IMO. So it makes sense to be cautious. Especially if you're in a higher risk population.
My understanding (per a paper in Nature) is that natural immunity from SARS still provided immunity to Covid almost 2 decades later. My guess is that a vaccine won't be a durable as that. And that it may not offer protection as broads as that. Would be interesting to see if the memory t cells for SARS still worked against Delta. Maybe the paper you linked looks at that for memory t cells for covid. I'll have to check it out.
But natural immunity to covid might not be that durable either, or as broad. And the positive predictive value of positive test probably isn't as high as we'd hope given the low prevalence, so a good number of positive tests will be false...which means many who think they had it didn't. It makes sense to try to bias toward false positives, because a false positive is much better than a false negative.
And it may be that mass vaccination during the pandemic is putting evolutionary pressure on the disease...while potentially removing the pressure to become less deadly since vaccinated people can still get and transmit without having serious symptoms.
There's a 2015 (?) paper in one of the PLOS journals that talks about this risk from imperfect vaccination (in some animal population.. Chickens I think?). Hopefully it's not applicable to what we're doing now.
But to me, that's the best argument for getting vaccinated. That vaccination of this type (i.e. leaky / imperfect) has a possibility of making new variants more deadly (especially to the unvaccinated).
I'm not saying that we shouldn't have run the experiment...we'll only know that for sure in hind sight. And you don't get access to a time machine when you're making decisions.
But it should be clear that we are running an experiment. And while we have hypotheses that make sense for what will happen (some good, some bad), I don't think we actually know if this will work in the medium to long term...but it's not exactly my field so I could be underestimating or level of understanding.
Maybe none of that matters. But I think it all adds up to "still try to be cautious". Part of that is behavior around getting vaccinated. Part of that is also losing weight (on my case anyway) and getting enough micronutrients (we stick at vitamin D here in the North East... Especially in the winter). And part of it is also trying to figure out how to deal with all of this without sacrificing mental health.
It's obvious that it's a difficult problem on a societal level.
And unfortunately it doesn't like to be as simple as "take two shots and it will all be over". That was never the promise... But I think it was the hope.
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